Cultured papilla cells

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Cultured dermal papilla cells induce follicle formation and hair growth by transdifferentiation of an adult epidermis.

Adult rat pelage follicle dermal papilla cells induced follicle neogenesis and external hair growth when associated with adult footpad skin epidermis. They thus demonstrated a capacity to completely change the structural arrangement and gene expression of adult epidermis--an ability previously undocumented for cultured adult cells. Isolation chambers ensured that de novo follicle formation must...

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Whisker growth induced by implantation of cultured vibrissa dermal papilla cells in the adult rat.

Retention of the capacity to induce the growth of hair by cultured adult rat vibrissa dermal papilla cells has been investigated. Small pellets of serially cultured papilla cells were implanted into the bases of the exposed follicular epidermis of amputated adult rat vibrissa follicles. Amputated follicles that received no cell implants or implants of cultured dorsal skin fibroblasts were used ...

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Evaluation of animal models for the hair-inducing capacity of cultured human dermal papilla cells.

BACKGROUND The dermal papilla (DP) interacts with epithelial cells for folliculogenesis. For translational research on cell therapies for hair regrowth with cultured human DP cells (hDPCs), a model to evaluate the capacity of hDPCs to induce hair formation is inevitable. METHODS Chamber models were constructed by transplanting 4 different combinations of mouse or human epithelial and mesenchy...

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Poor Capability of 3D-Cultured Adipose-Derived Stem Cells to Induce Hair Follicles in Contrast to 3D-Cultured Dermal Papilla Cells

662 Ann Dermatol Received April 3, 2015, Revised August 18, 2015, Accepted for publication September 24, 2015 Corresponding author: Young Kwan Sung, Department of Immunology, Kyungpook National University School of Medicine, 680 Gukchaebosangro, Jung-gu, Daegu 41944, Korea. Tel: 82-53-420-4874, Fax: 82-53-423-4628, E-mail: [email protected] This is an Open Access article distributed under the ter...

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Slow-cycling cells in renal papilla: stem cells awaken?

A fundamental goal of kidney stem cell models in regenerative medicine is to harness the kidney’s prodigious capacity for endogenous repair to develop new therapeutic strategies. Despite progress in understanding kidney injury and repair mechanisms, few regenerative therapies to treat human kidney injury are on the horizon. In part, this reflects the kidney’s complex architecture and cellular h...

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ژورنال

عنوان ژورنال: Juntendo Medical Journal

سال: 1992

ISSN: 0022-6769,2188-2134

DOI: 10.14789/pjmj.37.557